The U.S. Department of Health and Human Services (HHS) recently published two updates to its Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV (OI Guidelines) which include new information about the management of four infectious diseases – cytomegalovirus (CMV), cryptococcosis, coccidioidomycosis, and bartonellosis – in people with HIV. These updates incorporate the latest available information about the diagnosis and treatment of these infections in particular patient populations, as well as toxicities of certain antiviral medications used to treat CMV. The latest version of the guidelines also includes updates to HHS recommendations concerning immunizations for preventable diseases in adults and adolescents with HIV. 


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